@article{Büyükkıdan_ilkimen_Durmuş_Gülbandılar_2021, title={Synthesis and characterization of Cu(II) complexes of proton transfer salts derived from piperazine derivatives and 5-sulfosalicylic acid}, volume={40}, url={https://mjcce.org.mk/index.php/MJCCE/article/view/2411}, DOI={10.20450/mjcce.2021.2411}, abstractNote={<p>In this study, proton transfer salts (H<sub>2</sub>Etpip)(Hssa), (H<sub>2</sub>HOEtpip)(Hssa) and (HAcpip)(H<sub>2</sub>ssa), have been obtained by reactions between 1-ethylpiperazine (Etpip), 1-(2-hydroxyethyl)piperazine (HOEtpip) and 1‑acetylpiperazine (Acpip) and 5-sulfosalicylic acid (H<sub>3</sub>ssa). Also, Cu(II) complexes of proton transfer salts (H<sub>2</sub>Etpip)[Cu(Hssa)<sub>2</sub>]·5H<sub>2</sub>O, (H<sub>2</sub>HOEtpip)[Cu(Hssa)<sub>2</sub>]·5H<sub>2</sub>O and (H<sub>2</sub>Acpip)[Cu(Hssa)<sub>2</sub>]·5H<sub>2</sub>O) have been synthesized. The structures of proton transfer salts have been proposed by using FT-IR, <sup>1</sup>H and <sup>13</sup>C NMR spectroscopy, and elemental analysis. The structures of the amorphous metal complexes have been proposed by atomic absorption spectrometry, FT-IR, magnetic susceptibility, molar conductivity techniques, and elemental analysis. Antimicrobial activities of compounds have been tested against <em>Staphylococcus aureus</em> (ATCC 29213) (Gram-positive), <em>Escherichia coli</em> (ATCC 25922) (Gram-negative), <em>Candida krusei</em> (ATCC 6258) (yeast), and <em>Candida parapsilosis</em> (ATCC 22019) (yeast) microorganisms. For <em>S. aureus</em>, the minimum inhibitory concentration (MIC) values of the synthesized salts were between 31.25 and 62.50 µg/ml, and 15.60 µg/ml for complexes. The MIC values of salts and complexes for <em>E. coli</em> were in the range 125.00–500.00 µg/ml and 31.25–62.50 µg/ml, respectively. The MIC values of the salts for <em>C. krusei </em>were 62.50 µg/ml, and for the complexes in the range 15.60–31.25 µg/ml. For <em>C. parapsilosis</em>, these values were 31.25 µg/ml for all salts and in the range 15.60–62.50 µg/ml for complexes.</p>}, number={2}, journal={Macedonian Journal of Chemistry and Chemical Engineering}, author={Büyükkıdan, Nurgün and ilkimen, Halil and Durmuş, Büşra and Gülbandılar, Aysel}, year={2021}, month={Dec.}, pages={159–169} }