The Pd(II) complex involving a new pyrole-based ligand: Synthesis, spectral analysis and antimicrobial activity

Authors

  • Özlen Altun Department of Chemistry, Trakya University, Edirne
  • Mesut Boz Department of Chemistry, Trakya University, Edirne
  • Övul Tetik Department of Chemistry, Trakya University, Edirne

DOI:

https://doi.org/10.20450/mjcce.2022.2526

Keywords:

heterocyclic compounds, Palladium(II), Spectral characterization, Biological activity.

Abstract

In the current study, firstly, a new pyrrole-based ligand (3,4-(ethylenedimercaptodiacetoxy)-N-(benzyl)-diethyl-2,5-pyrroledicarboxylate (L) was synthesized in the presence of diethyl-N-benzyl-3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate and 2,2'-(ethane-1,2-diylbis(sulfanediyl))diacetylchloride. Then, the palladium(II) complex of the synthesized ligand was obtained, and its structural features were examined by spectral (HRMS, ESI-MS, UV-Visible, FTIR, 1H NMR, 13C NMR, XRD-POWDER, SEM, EDX) and thermogravimetric (TG-DTA) techniques. The spectral and thermal measurements of the ligand and its Pd(II) complex show that the ligand is coordinated to the Pd2+ ion. Antimicrobial activities of both the ligand and its palladium complex were examined. It was determined that whereas the ligand indicated modest antimicrobial activity against Staphylococcus aureus and Candida albicans at a concentration of 6.25 µg/ml, the palladium complex was significantly effective against C. albicans at a concentration of 6.25 µg/ml.

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2022-11-30 — Updated on 2022-12-31

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How to Cite

Altun, Özlen, Boz, M., & Tetik, Övul. (2022). The Pd(II) complex involving a new pyrole-based ligand: Synthesis, spectral analysis and antimicrobial activity. Macedonian Journal of Chemistry and Chemical Engineering, 41(2), 251–259. https://doi.org/10.20450/mjcce.2022.2526 (Original work published November 30, 2022)

Issue

Vol. 41 No. 2 (2022)

Section

Inorganic Chemistry

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Copyright (c) 2022 Özlen Altun, Mesut Boz, Övul Tetik

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