Response surface methodology approach for optimization of methyl orange adsorptive removal by magnetic chitosan nanocomposite

Ali Ayati, Ali Zeraatkar Moghaddam, Bahareh Tanhaei, Fatemeh Deymeh, Mika Sillanpaa


In this work, the adsorption process of methyl orange (MO) removal by a magnetic chitosan with an Al2O3/Fe3O4 core was optimized using the experimental design method in order to maximize the removal efficiency. Response surface methodology (RSM) based on central composite design (CCD) was performed to find the relationship between the effective adsorption parameters on the MO removal efficiency as the response. The statistical parameters of the derived model were acquired: R2 = 0.9799 and F value = 47.07. Finally, non-linear optimization was carried out and values of 6.5, 0.70 g l–1, 30 ppm, and 60 min were obtained as the optimum values for pH, adsorbent dosage, initial concentration, and contact time, respectively, while the predicted MO removal efficiency was found to be 96.8 ± 2.2% (with a 95% confidence level). This was in agreement with the experimental response of 96.5 ± 1.4%.


Adsorption; Optimization; Chitosan; Magnetic; Response Surface Methodology.

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C. Liu, R. Bai, Recent advances in chitosan and its de-rivatives as adsorbents for removal of pollutants from water and wastewater. Curr. Opin. Chem. Eng., 4, 62–70 (2014).

A. Bhatnagar, M. Sillanpää, Applications of chitin- and chitosan-derivatives for the detoxification of water and wastewater – A short review. Adv. Colloid Interface Sci., 152, 26–38 (2009).

H. Sashiwa, S. Aiba, Chemically modified chitin and chitosan as biomaterials. Prog. Polym. Sci., 29, 887–908 (2004).

E. Repo, J. K. Warchoł, A. Bhatnagar, A. Mudhoo, M. Sillanpää, Aminopolycarboxylic acid functionalized ad-sorbents for heavy metals removal from water. Water Res., 47, 4812–4832 (2013).

E. Repo, J. K. Warchol, T. A. Kurniawan, M. Sillanpää, Adsorption of Co(II) and Ni(II) by EDTA- and/or DTPA-modified chitosan: kinetic and equilibrium mod-eling. Chem. Eng. J., 161, 73–82 (2010).

N. M. Alves, J. F. Mano, Chitosan derivatives obtained by chemical modifications for biomedical and environ-mental applications. Int. J. Biol. Macromol., 43, 401–414 (2008).

W. S. W. Ngah, S. A. Ghani, A. Kamari, Adsorption behavior of Fe(II) and Fe(III) ions in aqueous solution on chitosan and cross-linked chitosan beads. Bioresource Technol., 96, 443–450 (2005).

M. Vakili, M. Rafatullah, B. Salamatinia, A. Z. Abdullah, M. H. Ibrahim, K. B. Tan, Z. Gholami, P. Amouzgar, Application of chitosan and its derivatives as adsorbents for dye removal from water and wastewater: A review. Carbohyd. Polym., 113, 115–130 (2014).

A. Ayati, B. Tanhaei, M. Sillanpää, Lead(II)-ion removal by ethylenediaminetetraacetic acid ligand functionalized magnetic chitosan-aluminum oxide-iron oxide nanoadsorbents and microadsorbents: Equilibrium, ki-netics, and thermodynamics. J. Appl. Polym. Sci., 134, 44360 (2016).

B. Tanhaei, A. Ayati, F. F. Bamoharram, M. Lahtinen, M. Sillanpää, A novel magnetic Preyssler acid grafted chitosan nano adsorbent: synthesis, characterization and adsorption activity. J. Chem. Technol. Biotechnol., 91, 1452–1460 (2016).

G. Crini, P. M. Badot, Application of chitosan, a natural aminopolysaccharide, for dye removal from aqueous so-lutions by adsorption processes using batch studies: A review of recent literature. Prog. Polymer Sci,, 33, 399–447 (2008).

F. Zhao, E. Repo, D. Yin, M. E. T. Sillanpää, Adsorption of Cd(II) and Pb(II) by a novel EGTA-modified chitosan material: Kinetics and isotherms. J. Colloid Interf. Sci., 409, 174–182 (2013).

D. H. K. Reddy, S. M. Lee, Application of magnetic chitosan composites for the removal of toxic metal and dyes from aqueous solutions. Adv. Colloid Interface Sci., 201-202, 68–93 (2013).

B. V. S. Reddy, G. Narasimhulu, P. S. Lakshumma, Y. V. Reddy, J. S. Yadav, Phosphomolybdic acid: a highly efficient solid acid catalyst for the synthesis of trans-4,5-disubstituted cyclopentenones. Tetrahedron Lett., 53, 1776–1779 (2012).

A. M. Donia, A. A. Atia, K. Z. Elwakeel, Selective sepa-ration of mercury(II) using magnetic chitosan resin mod-ified with Schiff’s base derived from thiourea and glutaraldehyde. J. Hazard. Mater., 151, 372–379 (2008).

R. D. Ambashta, M. Sillanpää, Water purification using magnetic assistance: A review. J. Hazard. Mater., 180, 38–49 (2010).

R. Hua, Z. Li, Sulfhydryl functionalized hydrogel with magnetism: Synthesis, characterization, and adsorption behavior study for heavy metal removal. Chem. Eng. J., 249, 189–200 (2014).

W. S. W. Ngah, L. C. Teong, M. A. K. M. Hanafiah, Adsorption of dyes and heavy metal ions by chitosan composites: a review. Carbohydr. Polym., 83, 1446–1456 (2011).

E. Repo, J. K. Warchoł, A. Bhatnagar, M. Sillanpää, Heavy metals adsorption by novel EDTA-modified chi-tosan-silica hybrid materials. J. Colloid Interface Sci., 358, 261–267 (2011).

B. Tanhaei, A. Ayati, M. Lahtinen, M. Sillanpää, Prepa-ration and Characterization of a Novel Chitosan/ Al2O3/Magnetite Nanoparticles Composite Adsorbent for Kinetic, Thermodynamic and Isotherm Studies of Methyl Orange Adsorption. Chem. Eng. J., 259, 1–10 (2015).

B. Tanhaei, A. Ayati, M. Lahtinen, B. M. Vaziri, M. Sillanpää, A magnetic mesoporous chitosan based core-shells biopolymer for anionic dye adsorption: kinetic and isothermal study and application of ANN. J. Appl. Polym. Sci. ,133, 43466 (2016).

N. Sivarajasekar, R. Baskar, Adsorption of basic red 9 on activated waste Gossypium hirsutum seeds: Process modeling, analysis and optimization using statistical de-sign. J. Ind. Eng. Chem., 20, 2699–2709 (2013).

G. Derringer, R. Suich, Simultaneous optimization of several response variables. J. Quality Technol., 12, 214–219 (1980).

D. C. Montgomery, Design and Analysis of Experiments. John Wiley, 2000.

D. O. Aksoy, E. Sagol, Application of central composite design method to coal flotation: Modelling, optimization and verification. Fuel, 183, 609–616 (2016).

N. Sivarajasekar, R. Baskar, Agriculture waste biomass valorisation for cationic dyes sequestration: A concise review. J. Chem. Pharm. Res. 7, 737–748 (2015).

N. Sivarajasekar, R. Baskar, Biosorption of basic violet 10 onto activated Gossypium hirsutum seeds: Batch and fixed-bed column studies. 23, 1610–1619 (2015).

N. Sivarajasekar, R. Baskar, Adsorption of Basic Ma-genta II onto H2SO4 activated immature Gossypium hirsutum seeds: Kinetics, isotherms, mass transfer, thermodynamics and process design. Arab. J. Chem., In Press, (2014).

A. Ayati, A. Ahmadpour, F. F. Bamoharram, M. Mänttäri, M. Sillanpää, A review on Catalytic Applica-tions of Au Nanoparticles in the Removal of Water Pol-lutant. Chemosphere, 107, 163–174 (2014).

A. Ayati, M. N. Shahrak, B. Tanhaei, M. Sillanpää, Emerging adsorptive removal of azo dye by metal-organic frameworks. Chemosphere, 160, 30–44 (2016).

G. Khoobbakht, G. Najafi, M. Karimi, A. Akram, Opti-mization of operating factors and blended levels of diesel, biodiesel and ethanol fuels to minimize exhaust emissions of diesel engine using response surface methodology. Appl. Thermal Eng., 99, 1006–1017 (2016).

V. Srivastava, Y. C. Sharma, M. Sillanpää, Application of response surface methodology for optimization of Co(II) removal from synthetic wastewater by adsorption on NiO nanoparticles. J. Mol. Liq., 211, 613–620 (2015).

V. Srivastava, Y. C. Sharma, M. Sillanpää, Response surface methodological approach for the optimization of adsorption process in the removal of Cr(VI) ions by Cu2(OH)2CO3 nanoparticles. Appl. Surf. Sci., 326, 257–270 (2015).

E. Morgan, Chemometrics: Experimental Design. Lon-don: Wiley, 1991.

M. Jalali-Heravi, H. Parastar, H. Ebrahimi-Najafabadi, Characterization of volatile components of Iranian saffron using factorial-based response surface modeling of ultrasonic extraction combined with gas chromatography –mass spectrometry analysis. J. Chromatogr. A, 1216, 6088–6097 (2009).

B. K. Korbahti, M. A. Rauf, Determination of optimum operating conditions of carmine decoloration by UV/H2O2 using response surface methodology. J. Haz-ard. Mater., 161, 281–286 (2009).

R. L. Mason, R. F. Gunst, J. J. Hess, Statistical Design and Analysis of Experiments with Applications to Engi-neering and Science. 2003, Hoboken: Wiley.



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