Metallomics related to gallium compounds: biochemical and xenobiochemical aspects

Zeno Gârban, Radu Silaghi-Dumitrescu, Gabriela Gârban, Adina Avacovici, Nicoleta Hădărugă, Cornel Baltă, George-Daniel Ghibu, Cristina Bischin, Olga-Alina Rada

Abstract


Issues concerning the chemical compounds studied in the framework of metallomics are of interest both for biochemistry – domain dealing with the metabolization of nutrients and xenobiochemistry – a subsequent domain of biochemistry dealing with the biodegradation of xenobiotics. In this context, reviewed here are in vivo and in vitro data on inorganic and organo-metallic compounds of gallium (Ga), ranging from cellular and molecular biology, to biochemistry and pathobiochemistry, and to pharmacology and related to homeostasis and nutrient degradation.

Keywords


gallium compounds – biochemistry; xenobiochemistry; biomedical effects; in vivo; in vitro

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DOI: http://dx.doi.org/10.20450/mjcce.2014.131

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